Mexicana is known to be a good strain for first-time users, the effects are described as a complete psychoactive experience with subtle effects on the body.
Everyone’s physiology and metabolism is different, and individual brain chemistry and body size play a significant role in how each individual might respond to psilocybin, as will your surroundings and emotional state, so if it is your first time or you are significantly upping your dosage, select a safe, comfortable, and if possible, familiar place, and consider asking a sober tripsitter to be your companion for the coming ride.
Effects begin between 10 to 40 minutes after ingestion and can last between 3 and 6 hours, depending on the dose and the individual. Like all tryptamines, psilocybes often cause what have been called “the mushroom yawns” which increase markedly as one begins to peak, however, the feeling in the rest of the body is energetic, not tired. Users can expect a wide variety of possible effects and sensations, from the mystical, euphoric and revelatory to the hyperspatial and mind-alteringly observational. At doses over 2 grams, some users report experiencing warping of the visual field, and Dali-esque melting objects, and other possible effects include time distortion, hallucinations both when eyes are closed or open and synesthesia (i.e. “seeing” sounds and “feeling” colours), particularly with the Transkei variety of cubensis, which also tends to have a heavier body load. Remember to stay hydrated, especially if you’re outdoors or doing activity like dancing, and try sipping some honey ginger tea to counteract any possible nausea during the come-up. Do not use if pregnant and do not mix with other drugs, especially alcohol.